Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human E2F3
Source
Monoclonal,Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Background
This gene encodes a member of a small family of transcription factors that function through
binding of DP interaction partner proteins. The encoded protein recognizes a specific
sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to
regulate the expression of genes involved in the cell cycle. Altered copy number and activity
of this gene have been observed in a number of human cancers. There are pseudogenes for
this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript
variants
