Reactive species
Human,Mouse,Rat
Gene Name
PHF15 JADE2 KIAA0239
Protein name
Protein Jade-2 (PHD finger protein 15)
Immunogen
Synthesized peptide derived from human PHF15
Specificity
This antibody detects endogenous levels of PHF15 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal,Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity . Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A . Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).
