Reactive species
Human,Mouse,Rat
Protein name
Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial (Endopeptidase Clp)
Immunogen
Synthesized peptide derived from human CLPP
Specificity
This antibody detects endogenous levels of CLPP at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal,Mouse,IgG
Dilution rate
WB 1:500-2000;
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates . Cleaves PINK1 in the mitochondrion .
