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K63-linkage Specific Polyubiquitin Mouse mAb

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Product code: YP-mAb-18798
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Product introduction

Reactive species
Human,Mouse,Rat
Applications
WB
Antibody type
单克隆抗体
Gene Name
Protein name
Dalton（DA）
15-200kDa
Immunogen
A synthetic peptide corresponding to a sequence containing polyubiquitinated protein
Specificity
Constitute
Source
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Concentration
1 mg/ml
Stockpile
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
Background
Ubiquitination,onetypeofthemostcommonposttranslationalmodification,mediatestheregulationofproteinhomeostasisinvivo.Sinceubiquitinits elfcontainsmultiplelysineresiduesandoneNterminalfreeaminogroup,eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development （PMID: 19217402，PMCID: PMC3008764
Function

Open

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