Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of
human MAML1 (NP_055572.1).
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
Mam1; Mam-1; MAML1
Background
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in
the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence
that the human homolog forms a complex with the intracellular portion of human Notch
receptors and can increase expression of a Notch-induced gene. This evidence supports its
proposed function as a transcriptional co-activator in the Notch signaling pathway
