Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-79 of human COX7A1
(NP_001855.1)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
COX7A; COX7AH; COX7AM; COX7A1
Background
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain,
catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a
heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and
multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded
subunits function in electron transfer, and the nuclear-encoded subunits may function in the
regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle
isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other
polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are
encoded by different genes.
