Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 51-170 of
human MCU (NP_612366.1).
Dilution rate
WB 1:1000-1:5000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
HsMCU; C10orf42; CCDC109A; MCU
Background
Enables calcium channel activity; identical protein binding activity; and uniporter activity.
Involved in several processes, including positive regulation of mitochondrial calcium ion
concentration; positive regulation of mitochondrial fission; and positive regulation of
neutrophil chemotaxis. Acts upstream of or within calcium import into the mitochondrion.
Located in mitochondrial inner membrane. Is integral component of mitochondrial inner
membrane. Part of uniplex complex
