Reactive species
Human,Mouse,Rat
Immunogen
A synthetic phosphorylated peptide around T389 of human P70 S6K (NP_003152.1).
Dilution rate
WB 1:500 - 1:1000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha;
Phospho-p70 S6 Kinase 1-T389
Background
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases.
The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to
promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been
associated with human cancer. Alternatively spliced transcript variants have been observed.
The use of alternative translation start sites results in isoforms with longer or shorter Ntermini which may differ in their subcellular localizations. There are two pseudogenes for this
gene on chromosome 17.
