Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2645-2813
of human von Willebrand factor (VWF) (NP_000543.3)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
VWD; F8VWF; von Willebrand factor (VWF)
Background
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is
proteolytically processed following assembly into large multimeric complexes. These
complexes function in the adhesion of platelets to sites of vascular injury and the transport
of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an
inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome
22
