Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 196-345 of
human NDUFAF5 (NP_077025.2).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Other name
C20orf7; MC1DN16; dJ842G6.1; bA526K24.2; NDUFAF5
Background
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory
chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least
43 subunits. The complex is located in the inner mitochondrial membrane. This gene
encodes a mitochondrial protein that is associated with the matrix face of the mitochondrial
inner membrane and is required for complex I assembly. A mutation in this gene results in
mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms
have been found for this gene.