Background
This gene encodes a member of a family of protein kinases that are involved in the
integration of biochemical signals for a wide variety of cellular processes, including cell
proliferation, differentiation, transcriptional regulation, and development. The encoded
protein can be activated by proinflammatory cytokines and environmental stresses through
phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing
results in multiple transcript variants. [provided by RefSeq, Mar 2014]
