Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKD1
(NP_149110.1).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Background
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as
a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf
(see MIM 602272) signaling pathway.
