Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 234-323 of
human DEGS1 (NP_003667.1).
Dilution rate
WB 1:1000- 1:3000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Other name
MLD; DEGS; DES1; Des-1; FADS7; HLD18; MIG15; DEGS-1; DEGS1
Background
This gene encodes a member of the membrane fatty acid desaturase family which is
responsible for inserting double bonds into specific positions in fatty acids. This protein
contains three His-containing consensus motifs that are characteristic of a group of
membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning
protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited
biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in
regulating biosynthetic processing of the EGF receptor.
