Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence containing polyubiquitinated protein (K29
linkage).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Background
Polyubiquitin chains regulate diverse cellular processes through the ability of ubiquitin to
form chains of eight different linkage types. when attached to a target protein, have
different functions depending on the Lys residue of the ubiquitin that is linked. K29-linked
ubiquitination is involved in different kinds of cellular proteotoxic stress response as well as
cell cycle regulation. In particular, K29-linked ubiquitination is enriched in the midbody and
downregulation of the K29-linked ubiquitination signal arrests cells in G1/S phase.
