Reactive species
Human,Mouse,Rat
Protein name
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Immunogen
Synthesized peptide derived from human RGS3
Specificity
This antibody detects endogenous levels of RGS3 at Human, Mouse,Rat
Constitute
This antibody detects endogenous levels of RGS3 at Human, Mouse,Rat
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
