Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 410-600 of
human PI3 Kinase p110 beta (NP_006210.1)
Dilution rate
WB 1:2000- 1:8000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
PI3K; PIK3C1; P110BETA; PI3KBETA; PI3 Kinase p110 beta
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K).
These kinases are important in signaling pathways involving receptors on the outer
membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein
is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the
activation pathway in neutrophils which have bound immune complexes at sites of injury or
infection. Alternative splicing results in multiple transcript variants.
