Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of
human PDC (NP_002588.3).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
PHD; MEKA; PhLP; PhLOP; PDC
Background
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the
rod cells in the retina. This protein may participate in the regulation of visual
phototransduction or in the integration of photoreceptor metabolism. It modulates the
phototransduction cascade by interacting with the beta and gamma subunits of the retinal
G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and
Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms
have been identified.
