Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 5000-5100 of human MUC2 (Q02817).
Dilution rate
WB 1:000-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
MLP; SMUC; MUC-2; MUC2
Background
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is
secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein
polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight.
The protein features a central domain containing tandem repeats rich in threonine and
proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis.
