Reactive species
Human,Mouse,Rat
Gene Name
AP5Z1 KIAA0415 SPG48
Protein name
AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5)
Immunogen
Synthesized peptide derived from human AP5Z1/SPG48
Specificity
This antibody detects endogenous levels of AP5Z1/SPG48 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Function
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair.
