Reactive species
Human,Mouse,Rat
Dalton（DA）
Calculated MW: 44 kDa; Observed MW: 53 kDa
Immunogen
A synthesized peptide derived from human TXNIP
Dilution rate
WB: 1/500-1/1000
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
HHCPA78; THIF; TXNIP; VDUP1
Background
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm.
