Reactive species
Human;Mouse
Protein name
Cyclin-dependent kinases regulatory subunit 1
Immunogen
The antiserum was produced against synthesized peptide derived from human CKS1. AA range:10-59
Specificity
Cks1 Monoclonal Antibody detects endogenous levels of Cks1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CKS1B; CKS1; PNAS-143; PNAS-16; Cyclin-dependent kinases regulatory subunit 1; CKS-1
Background
CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008],
Function
function:Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.,similarity:Belongs to the CKS family.,subunit:Forms a homohexamer that can probably bind six kinase subunits.,
