Reactive species
Human;Mouse;Rat
Protein name
DNA replication licensing factor MCM5
Immunogen
The antiserum was produced against synthesized peptide derived from human MCM5. AA range:21-70
Specificity
CDC46 Monoclonal Antibody detects endogenous levels of CDC46 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46
Background
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,
