Reactive species
Human;Rat;Mouse;
Protein name
Son of sevenless homolog 2
Immunogen
The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680
Specificity
Sos 2 Monoclonal Antibody detects endogenous levels of Sos 2 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
SOS2; Son of sevenless homolog 2; SOS-2
Background
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],
Function
function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain.,
