Reactive species
Human;Rat;Mouse;
Protein name
Ras association domain-containing protein 6
Immunogen
The antiserum was produced against synthesized peptide derived from human RASSF6. AA range:129-178
Specificity
RASSF6 Monoclonal Antibody detects endogenous levels of RASSF6 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
RASSF6; Ras association domain-containing protein 6
Background
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012],
Function
function:May act as a Ras effector protein.,sequence caution:Translated as Gln.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,
