Reactive species
Human;Rat;Mouse;
Protein name
Guanylate-binding protein 4
Immunogen
The antiserum was produced against synthesized peptide derived from human GBP4. AA range:551-600
Specificity
GBP4 Monoclonal Antibody detects endogenous levels of GBP4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
GBP4; Guanylate-binding protein 4; GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4
Background
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008],
Function
function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.,similarity:Belongs to the GBP family.,