Reactive species
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human OGN. AA range:231-280
Specificity
Osteoglycin Monoclonal Antibody detects endogenous levels of Osteoglycin protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
OGN; OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF
Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function
function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class III subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Bone.,
