Reactive species
Human;Rat;Mouse;
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of
human IGFBP7
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Other name
AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; IGFBP7
Background
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP)
family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and
tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with
relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates
prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding
different isoforms have been described for this gene, and one variant has been associated
with retinal arterial macroaneurysm (PMID:21835307).
