Reactive species
Human;Rat;Mouse;
Protein name
Choriogonadotropin subunit beta
Immunogen
The antiserum was produced against synthesized peptide derived from human hCG beta. AA range:101-150
Specificity
Choriogonadotropin β Monoclonal Antibody detects endogenous levels of Choriogonadotropin β protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CGB; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta
Background
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008],
Function
developmental stage:Made by the first trimester placenta.,function:Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.,online information:Chorionic gonadotropin entry,pharmaceutical:Available under the names Novarel (Ferring) and Profasi (Serono). Used as adjunctive therapy in the treatment of obesity. There is no substantial evidence that it increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or 'normal' distribution of fat, or that it decreases the hunger and discomfort associated with calorie-restricted diets.,similarity:Belongs to the glycoprotein hormones subunit beta family.,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.,tissue specificity:Placenta.,
