Reactive species
Human;Rat;Mouse;
Protein name
Phosphatase and actin regulator 4
Immunogen
The antiserum was produced against synthesized peptide derived from human PHACTR4. AA range:363-412
Specificity
PHACTR4 Monoclonal Antibody detects endogenous levels of PHACTR4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
PHACTR4; Phosphatase and actin regulator 4
Background
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase and actin regulator family.,similarity:Contains 3 RPEL repeats.,subunit:Binds PPP1CA and actin.,
