Background
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds
metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue
distribution of the expressed gene suggests that it is involved in the regulation of endocrine
function, and this is supported by the finding that this gene appears to play a role in the
onset of puberty. Mutations in this gene have been associated with hypogonadotropic
hypogonadism and central precocious puberty
