Reactive species
Human;Rat;Mouse;
Protein name
Melatonin-related receptor
Immunogen
The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350
Specificity
GPR50 Monoclonal Antibody detects endogenous levels of GPR50 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
Background
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],
Function
function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary.,
