Background
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to
melanosomes in pigment cells. This protein is thought to be involved in intracellular signal
transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred
to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene
has been identified on chromosome Y.
