Reactive species
Human; Mouse;Rat
Immunogen
Synthesized peptide derived from human THIC AA range: 320-370
Specificity
This antibody detects endogenous levels of THIC at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
Background
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],
Function
catalytic activity:2 acetyl-CoA = CoA + acetoacetyl-CoA.,similarity:Belongs to the thiolase family.,subunit:Homotetramer.,