Reactive species
Human;Rat;Mouse;
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of
human/mouse Integrin alpha 1/CD49a(NP_852478.1)
Dilution rate
WB 1:12500 - 1:50000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Background
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes
with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The
heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation
and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain
which is thought to be involved in collagen binding.
