Reactive species
Human; Mouse;Rat
Immunogen
Synthesized peptide derived from human ATG13 AA range: 182-232
Specificity
This antibody detects endogenous levels of ATG13 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.19% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:1000-2000
Purification process
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
Other name
Autophagy-related protein 13
Background
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
