Reactive species
Human; Mouse;Rat
Immunogen
Synthesized peptide derived from human PDK4 AA range: 34-84
Specificity
This antibody detects endogenous levels of PDK4 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:1000-2000
Purification process
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
Other name
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
Background
Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis.
