Reactive species
Human;Rat;Mouse;
Gene Name
SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL
Protein name
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SCRIB Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Function
similarity:Contains 4 PDZ (DHR) domains.,
