Reactive species
Human;Mouse;Rat
Protein name
Protein reprimo
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
RPRM Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
Function
function:May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex.,induction:By TP53/p53, following X-ray irradiation.,miscellaneous:'Reprimo' signifies stop/repress.,similarity:Belongs to the reprimo family.,
