Reactive species
Human;Mouse
Protein name
Ribonuclease 4 (RNase 4) (EC 3.1.27.-)
Immunogen
Synthesized peptide derived from human protein . at AA range: Internal
Specificity
RNAS4 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013],
Function
function:This RNase has marked specificity towards the 3' side of uridine nucleotides.,similarity:Belongs to the pancreatic ribonuclease family.,