Reactive species
Human;Mouse
Gene Name
SEMA6A KIAA1368 SEMAQ
Protein name
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 430-510
Specificity
SEM6A Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011],
Function
function:Can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Active as a homodimer or oligomer. Interacts with EVL.,
