Reactive species
Human;Mouse;Rat
Gene Name
TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431
Protein name
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TAOK2 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Found to be perinuclear and localized to vesicular compartment.,subunit:Interacts with MKK3 and MKK6 (By similarity). Self-associates.,tissue specificity:Ubiquitously expressed, with a higher level of expression in testis and brain.,
