Reactive species
Human;Rat;Mouse;
Protein name
ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
ARL11 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010],
Function
disease:Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400].,function:May play a role in apoptosis. May act as a tumor suppressor.,similarity:Belongs to the small GTPase superfamily. Arf family.,tissue specificity:Expressed in lung and leukocytes.,
