Reactive species
Human;Mouse;Rat
Gene Name
GKN2 BLOT GDDR TFIZ1 UNQ465/PRO813
Protein name
Gastrokine-2 (Blottin) (Down-regulated in gastric cancer) (Trefoil factor interactions(z) 1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
GKN2 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015],
Function
similarity:Contains 1 BRICHOS domain.,subunit:Interacts with TFF2 (By similarity). Heterodimer with TFF1; disulfide linked.,tissue specificity:Expressed in gastric mucosa.,
