Reactive species
Human;Rat;Mouse;
Gene Name
TSHZ3 KIAA1474 TSH3 ZNF537
Protein name
Teashirt homolog 3 (Zinc finger protein 537)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TSH3 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016],
Function
function:Transcriptional regulator involved in developmental processes .,similarity:Belongs to the teashirt C2H2-type zinc-finger protein family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 5 C2H2-type zinc fingers.,
