Reactive species
Human;Rat;Mouse;
Gene Name
MAGED4 KIAA1859 MAGED4A MAGEE1; MAGED4B
Protein name
Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen)
Immunogen
Synthesized peptide derived from human protein . at AA range: 300-380
Specificity
MAGD4 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
MAGE family member D4B(MAGED4B) Homo sapiens This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes on chromosome Xp11. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011],
Function
similarity:Contains 1 MAGE domain.,tissue specificity:Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples.,