Reactive species
Human;Rat;Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SNPH Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Function
function:Inhibits SNARE complex formation by absorbing free syntaxin-1.,similarity:Belongs to the rad21 family.,subunit:Binds to syntaxin-1.,tissue specificity:Brain specific. Found in synapses.,
