Reactive species
Human;Mouse
Gene Name
SCARA5 UNQ2938/PRO28700
Protein name
Scavenger receptor class A member 5 (Scavenger receptor hlg)
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Specificity
SCAR5 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).,similarity:Belongs to the SCARA5 family.,similarity:Contains 1 collagen-like domain.,similarity:Contains 1 SRCR domain.,subunit:Homotrimer.,
Function
function:Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).,similarity:Belongs to the SCARA5 family.,similarity:Contains 1 collagen-like domain.,similarity:Contains 1 SRCR domain.,subunit:Homotrimer.,
