Reactive species
Human;Mouse
Gene Name
NUDCD3 KIAA1068
Protein name
NudC domain-containing protein 3
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
NUDC3 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CS domain.,
