Reactive species
Human;Rat;Mouse
Protein name
Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I)
Immunogen
Synthesized peptide derived from human protein . at AA range: 170-250
Specificity
NPTX1 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008],
Function
cofactor:Binds 2 calcium ions per subunit.,function:May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.,similarity:Contains 1 pentaxin domain.,
