Reactive species
Human;Mouse
Protein name
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
NMB Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],
Function
function:Stimulates smooth muscle contraction in a manner similar to that of bombesin.,similarity:Belongs to the bombesin/neuromedin-B/ranatensin family.,
